MOSAIC
Mathematical Oncology Systems Analysis Imaging Consortium
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A Centralized Curation of Image-Localized and
Multi-regional Tissue Sampling of Brain Tumors
We are a community of scientists interested in multi-regional sampling of brain tumors to reveal and study the heterogeneity within (brain) tumors.
This site acts as a service to the broader cancer biology community in which existing and new/novel tissue cohorts will be curated.
Our vision is that this open science initiative will embolden new discoveries in our pursuit of solving brain cancer!
March 2026: We have a further 236 samples from 35 patients with bulk RNA-Seq and 80 IDHmut samples from 12 patients with snRNA-Seq.
Jan 2025: We have since extended the cohort with 45 additional samples from 14 patients, leading to a total of 202 samples. We are in the process of aligning all this data to the new T2T reference genome to better discern sex differences.
May 2023: Our first novel cohort was collected by the Swanson Lab at Mayo Clinic in Phoenix, Arizona includes 157 MRI-localized biopsy samples from 44 patients with primary or recurrent glioblastoma highlighted in the following manuscript with bulk RNAseq and whole exome sequencing with metadata connecting these samples with imaging location.
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