Publications

Wang H, Argenziano MG, Yoon H, Boyett D, Save A, Petridis P, Savage W, Jackson P, Hawkins-Daarud A, Tran N, Hu L, Al Dalahmah O, Bruce JN, Grinband J, Swanson KR, Canoll P, Li J. Biologically-informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post-treatment glioblastoma. NPJ Digit Med. 2024;7:292. doi:10.1038/s41746-024-01277-4.

Wang L, Wang H, D’Angelo F, Curtin L, Sereduk CP, Leon G, Singleton KW, Urcuyo J, Hawkins-Daarud A, Jackson PR, Krishna C, Zimmerman RS, Patra DP, Bendok BR, Smith KA, Nakaji P, Donev K, Baxter LC, Mrugała MM, Ceccarelli M, Iavarone A, Swanson KR, Tran NL, Hu LS, Li J. Quantifying intra-tumoral genetic heterogeneity of glioblastoma toward precision medicine using MRI and a data-inclusive machine learning algorithm. PLoS One. 2024;19(4):e0299267. doi:10.1371/journal.pone.0299267. PMID:38568950; PMCID:PMC10990246.

Quiñones-Hinojosa A, Basil A, Moniz-Garcia D, Suarez-Meade P, Ramos A, Jentoft M, Middlebrooks E, Grewal S, Abode-Iyamah K, Bydon M, Sarkaria J, Dickson D, Swanson K, Rosenfeld S, Schiapparelli P, Guerrero-Cazares H, Chaichana K, Meyer F. From the operating room to the laboratory: role of the neuroscience tissue biorepository in the clinical, translational, and basic science research pipeline. Mayo Clin Proc. 2024;99(2):229-240. doi:10.1016/j.mayocp.2023.10.016. PMID:38309935; PMCID:PMC10842257.

Dadario NB, Boyett DM, Teasley DE, Chabot PJ, Winans NJ, Argenziano MG, Sperring CP, Canoll P, Bruce JN. Unveiling the inflammatory landscape of recurrent glioblastoma through histological-based assessments. Cancers (Basel). 2024;16(19):3283. doi:10.3390/cancers16193283. PMID:39409905; PMCID:PMC11476027.

Mao L, Wang L, Hu LS, Eschbacher JM, DeLeon G, Curtin LA, Urcuyo J, Sereduk C, Tran NL, Hawkins-Daarud A, Swanson KR, Li J. Weakly-supervised transfer learning with application in precision medicine. IEEE Trans Autom Sci Eng. 2024;21(4):6250-6264. doi:10.1109/TASE.2023.3323773. PMID:40757183; PMCID:PMC12312616.

Mao L, Wang H, Hu L, Tran NL, Canoll PD, Swanson KR, Li J. Knowledge-informed machine learning for cancer diagnosis and prognosis: a review. IEEE Trans Autom Sci Eng. 2024;22:10008-10028. doi:10.1109/TASE.2024.3515839. PMID:40893871; PMCID:PMC12393176.

von Reppert M, Ramakrishnan D, Brüningk SC, Memon F, Abi Fadel S, Maleki N, Bahar R, Avesta AE, Jekel L, Sala M, Lost J, Tillmanns N, Kaur M, Aneja S, Fathi Kazerooni A, Nabavizadeh A, Lin M, Hoffmann KT, Bousabarah K, Swanson KR, Haas-Kogan D, Mueller S, Aboian MS. Comparison of volumetric and 2D-based response methods in the PNOC-001 pediatric low-grade glioma clinical trial. Neurooncol Adv. 2024;6(1):vdad172. doi:10.1093/noajnl/vdad172. PMID:38221978; PMCID:PMC10785766.

Goldberg AR, Dovas A, Torres D, Pereira B, Das Sharma S, Mela A, Merricks EM, Megino-Luque C, McInvalle JJ, Olabarria M, Shokooh LA, Zhao HT, Chen C, Kotidis C, Calvaresi P, Banu MA, Razavilar A, Sudhakar TD, Saxena A, Chokran C, Humala N, Mahajan A, Xu W, Metz JB, Bushong EA, Boassa D, Ellisman MH, Hillman EMC, Hargus G, Bravo-Cordero JJ, McKhann GM II, Gill BJA, Rosenfeld SS, Schevon CA, Bruce JN, Sims PA, Peterka DS, Canoll P. Glioma-induced alterations in excitatory neurons are reversed by mTOR inhibition. Neuron. 2025;113(6):858-875.e10. PMID:39837324; PMCID:PMC11925689.

Banu MA, Dovas A, Argenziano MG, Zhao W, Sperring CP, Cuervo Grajal H, Liu Z, Higgins DM, Amini M, Pereira B, Ye LF, Mahajan A, Humala N, Furnari JL, Upadhyayula PS, Zandkarimi F, Nguyen TT, Teasley D, Wu PB, Hai L, Karan C, Dowdy T, Razavilar A, Siegelin MD, Kitajewski J, Larion M, Bruce JN, Stockwell BR, Sims PA, Canoll P. A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma. EMBO J. 2024;43(20):4492-4521. doi:10.1038/s44318-024-00176-4. PMID:39192032; PMCID:PMC11480389.

Huang D, Mela A, Bhanu NV, Garcia BA, Canoll P, Casaccia P. PDGF-BB overexpression in p53-null oligodendrocyte progenitors increases H3K27me3 and induces transcriptional changes that favor proliferation. Neoplasia. 2024;57:101042. doi:10.1016/j.neo.2024.101042. PMID:39216363; PMCID:PMC11402553.

Seong M, Bak-Gordon P, Liu Z, Canoll PD, Manley JL. Splicing dysregulation in glioblastoma alters the function of cell migration-related genes. Glia. 2025;73(2):251-270. doi:10.1002/glia.24630. PMID:39448549; PMCID:PMC11663109.

Urcuyo JC, Curtin L, Langworthy JM, De Leon G, Anderies B, Singleton KW, Hawkins-Daarud A, Jackson PR, Bond KM, Ranjbar S, Lassiter-Morris Y, Clark-Swanson KR, Paulson LE, Sereduk C, Mrugala MM, Porter AB, Baxter L, Salomao M, Donev K, Hudson M, Meyer J, Zeeshan Q, Sattur M, Patra DP, Jones BA, Rahme RJ, Neal MT, Patel N, Kouloumberis P, Turkmani AH, Lyons M, Krishna C, Zimmerman RS, Bendok BR, Tran NL, Hu LS, Swanson KR. Image-localized biopsy mapping of brain tumor heterogeneity: a single-center study protocol. PLoS One. 2023;18(12):e0287767. doi:10.1371/journal.pone.0287767. PMID:38117803; PMCID:PMC10732423.

Haile H, Leskinen S, Adapa AR, Goldberg AR, Viswanathan A, Milligan C, Conboy K, Schevon C, Canoll P, Gill BJA. The role of mTOR signaling in tumor-induced alterations to neuronal function in diffusely infiltrating glioma. Biomedicines. 2025;13(11):2593. doi:10.3390/biomedicines13112593. PMID:41301687; PMCID:PMC12650052.

Lee J, Chung Y-M, Silver DJ, Hao Y, Harwood DSL, Ealy A, Serapiglia AM, Curtin L, Benedetti JR, Ballard CAP, Lapsley K, Alvarez-Vazquez A, Goldberg J, Li C, Kaur S, Neal R, Wang SZ, Kay KE, Volovetz J, Hong ES, Fodor R, Jarmula J, Nicosia M, Rubin JB, Swanson KR, Ostrom QT, Panicker N, Kristensen BW, Berens M, Sharifi N, Lathia JD. Androgen loss accelerates brain tumour growth via HPA axis activation. Nature. 2026. doi:10.1038/s41586-026-10451-5. PMID:42092136.

Rifkin RA, Wu X, Pereira B, Gill BJ, Merricks EM, Michalak AJ, Goldberg AR, Humala N, Dovas A, Rai G, McKhann GM, Slesinger PA, Canoll P, Schevon C. A selective small-molecule agonist of G protein-gated inwardly rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures. Neuropharmacology. 2025;265:110259. doi:10.1016/j.neuropharm.2024.110259. PMID:39662702; PMCID:PMC11726401.

Haile H, Shlobin NA, Adapa AR, Leskinen S, Canoll P, Schevon C, McKhann GM, Gill BJA. Seizure outcomes as an understudied metric in glioma clinical trials: a review of the ClinicalTrials.gov database. Neurooncol Adv. 2026;8(1):vdaf237. doi:10.1093/noajnl/vdaf237. PMID:41613045; PMCID:PMC12848232.